
Anti-RELA 单克隆抗体
产品名称: Anti-RELA 单克隆抗体
英文名称: Anti-RELA Monoclonal Antibody
产品编号: K000210M
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-05-30T15:53:18
使用范围: WB IP IF IHC
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-RELA Monoclonal Antibody
品牌:solarbio | 货号:K000210M
宿主 | Mouse |
---|---|
英文名称 | Anti-RELA Monoclonal Antibody |
别名 | NFKB3;p65;NFkB p65 |
应用 | WB IP IF IHC |
稀释比例 | WB 1:500-2000. IP 1:200. IF 1:100-200. IHC 1:200-500. |
蛋白分子量 | 59/60kDa |
Gene ID | 5970 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Saturated ammonium sulfate precipitation |
亚型 | IgG1 |
免疫原 | Recombinant Protein |
性状 | 液体 |
Public Immunogen Range | Recombinant Protein |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | Q04206 |
克隆号 | 5G6 |
克隆类型 | Monoclonal Antibody |
背景资料 | NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection. |